Pragmatic Clinical Trials

We help define, design and improve pragmatic clinical trials.

Pragmatic Clinical Trials (PCTs) are designed to evaluate the risks and benefits of health interventions with the information needs of end users such as patients, doctors or payers, in mind. In contrast to explanatory trials, which evaluate how well medical products work under optimal circumstances in a carefully chosen, treatment-adherent patient group, PCTs generally include a broader range of patients and study sites, including community settings. These trials address practical questions about the risks, benefits, and costs of an intervention as they would occur in routine clinical practice.

You can find details on all of our PCT projects in the Pragmatic Clinical Trials section of our  Resource Center.